Maximum dose: 25 mg within a 48 hour periodĬoncomitant administration with CYP450 3A4 inhibitors (ketoconazole, itraconazole, saquinavir) or erythromycin:.Patients should be stable on alpha blocker therapy prior initiating treatment with this drug.Ĭoncomitant administration with ritonavir:.Initial dose: 25 mg orally 1 hour prior to sexual activity.Severe hepatic dysfunction (Child-Pugh Class C): Has not been studiedĬoncomitant administration with alpha blockers:.Mild to moderate hepatic dysfunction (Child-Pugh Class A and B): No adjustment recommended.Initial dose: 25 mg orally should be considered in patients with any degree of hepatic impairment.Severe renal dysfunction (CrCl less than 30 mL/min): 25 mg orally once a day 1 hour prior to sexual activity.Mild to moderate renal dysfunction (CrCl 30 to less than 80 mL/min): No adjustment recommended.Use: Treatment of erectile dysfunction Renal Dose Adjustments Initial dose: 25 mg orally once a day 1 hour prior to sexual activity Use: Treatment of PAH (WHO Group I) in adults to improve exercise ability and delay clinical worsening Usual Geriatric Dose for Erectile Dysfunction A 10 mg injection dose is predicted to provide pharmacological effect equivalent to the 20 mg oral dose.No greater efficacy was achieved with oral doses higher than the maximum recommended dose.Initial dose: 2.5 or 10 mg IV bolus three times a day.Maximum dose: 20 mg orally three times a day.Initial dose: 5 or 20 mg orally three times a day, 4 to 6 hours apart.

Use: Treatment of erectile dysfunction Usual Adult Dose for Pulmonary Hypertension Maintenance: 25 to 100 mg orally once a day, as needed, 1 hour prior to sexual activityĬomments: This drug may be taken anywhere from 30 minutes to 4 hours before sexual activity. Initial dose: 50 mg orally once a day, as needed, 1 hour prior to sexual activity Usual Adult Dose for Erectile Dysfunction

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